The integration of sensing and communication (ISAC) is emerging as a cornerstone technology for 6G, promising unprecedented capabilities. This technical presentation focuses on leveraging MATLAB to explore and refine ISAC paradigms for 6G. We will discuss the design workflows in MATLAB that enable the modeling of complex ISAC scenarios, performance evaluation, and the development of novel algorithms from seamless integrated operation to effective coexistence. This presentation aims to equip researchers and practitioners with the insights and tools necessary to navigate the challenges of ISAC, leveraging MATLAB's robust capabilities to drive innovation in 6G research.