Lecture
Electromembrane extraction – a novel, efficient, and environmentally friendly sample preparation technique
- at -
- B1.131
- Type: Lecture
Lecture description
Electromembrane extraction (EME) is a novel, one-step sample preparation technique designed for the extraction of charged analytes from aqueous samples, namely for bioanalysis. EME operates by facilitating extraction across a thin liquid membrane into an aqueous acceptor solution, forced by an electrical field. EME is applicable for drugs, metabolites, peptides, heavy metal ions, from whole blood, plasma/serum, urine, tissue samples, and other types of samples such as wastewater. The extraction mechanism effectively removes analytes from proteins, salts, phospholipids, and undesired endogenous compounds present in the sample, resulting in virtually no ion suppression in LC-MS and decreased down-time due to maintenance and cleaning. EME also represents very green chemistry, as only 3-10 µL of safe and non-volatile organic solvents is used per sample. In this presentation, the principle and advantages of EME will be introduced and discussed. The discussion will feature practical aspects of operation, generic methods, extraction performance and clean-up efficiency, example applications, and offer some future perspectives.
