Prof. Dr. Roman Fischer

Roman Fischer is an associate professor at the Target Discovery Institute (TDI) and Centre of Medicines Discovery (CMD) at the Nuffield Department of Medicine at the University of Oxford. He leads 2 proteomics focussed laboratories: the Discovery Proteomics Facility (DisPro, Academic Lead) and the Clinical Proteomics Group (CPG, Principal Investigator). DisPro engages in fundamental research collaborations involving protein-protein interactions, deep proteomes and PTM analysis using top end proteomics equipment (Orbitrap Astral, Orbitrap Ascend, TimsTOF HT, Q-Exactive). In the Clinical Research Group, RF focusses on own research interests covering the technology driven disciplines of spatial and single cell proteomics as well as high-throughput proteomics. The dedicated lab uses a TimsTOF Ultra 2, TimsTOF Flex, Leica LMD7, Leica Mica and CellenOne to develop specific workflows and address spatial proteome organisation in pathology, with a focus on cancer and its triggered immune response in specific cell compartments of the immune system. RF has published >250 peer reviewed manuscripts, which acquired >18000 citations (h-index 67) and is an established leader in the field of proteomics with >20 years of experience in this area. DisPro and CPG have links to all major hospitals in Oxford and long-standing collaborations with most departments across the University, facilitating close interaction and collaboration with clinical PIs with access to study and trial samples.