Lecture

Next-Gen HPLC: A Column Technology Deep Dive

  • at -
  • ICM Saal 5
  • Type: Lecture

Lecture description

Column technology remains at the forefront of chromatographic advancements,
enabling greater resolution, speed, and efficiency in separations. This lecture will
explore the state-of-the-art innovations shaping the field, focusing on three
transformative developments: micro-pillar array columns, 3D-printed chromatographic
supports, and multi-capillary channel systems.

Micro-pillar array columns represent a paradigm shift in stationary phase
design. By employing precisely engineered microstructures, these columns deliver
superior separation efficiency, reduced backpressure, and enhanced reproducibility.
Their potential applications in high-throughput and miniaturized analytical workflows
will be discussed, highlighting their compatibility with modern liquid chromatography
systems.

Additive manufacturing has revolutionized chromatographic support fabrication.
The advent of 3D printing enables the creation of intricate and customizable stationary
phases with unprecedented control over geometry and porosity. This lecture will
examine how these supports enhance mass transfer, reduce eddy diffusion, and
expand the horizons for novel stationary phase chemistries.

Finally, multi-capillary channel columns introduce a multi-dimensional approach
to chromatographic separation. By leveraging parallel capillary pathways, these
systems achieve faster analyses without compromising resolution. Key insights into
their design, integration with existing chromatography platforms, and potential for ultrafast
separations will be presented.

Together, these innovations underscore the rapid evolution of column technology,
addressing the growing demands for efficiency, sensitivity, and sustainability in
analytical separations. Attendees will gain an understanding of these cutting-edge
developments and their implications for future research and industrial applications.
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