Lecture
Monitoring of persistent, mobile substances in aquatic systems using different chromatographic separations coupled to high-resolution mass spectrometry
- at -
- ICM Saal 3
- Type: Lecture
Lecture description
J. Hollender, Dübendorf, CH, J. Schorr, Dübendorf, CH, C. Meyer, Dübendorf, CH.
Persistent and mobile (PM), and very persistent and very mobile (vPvM) substances pose a threat to the water cycle but are often not covered in conventional environmental monitoring programs. PM substances that enter surface waters through
agricultural runoff and wastewater discharges can penetrate natural barriers such as soil and riverbanks, reach groundwater resources, and even pass drinking water treatment steps including activated carbon or ozonation. Many PM substances are not
covered by routine reversed-phase solid phase extraction followed by reverse-phase liquid chromatography coupled to mass spectrometry [1].
In this presentation, enrichment steps and chromatographic separations such as anion chromatography [2], hydrophilic interaction chromatography and mixed-mode liquid chromatography suitable for monitoring of anionic and small neutral PM substances
such as pesticide transformation products and industrial contaminants will be discussed. Coupling with high resolution mass spectrometry enables an expansion from target to suspect and non-target screening, closing the monitoring gap. The challenges and limitations of the methods will be illustrated using various water samples.
Literature:
[1] Zahn, D., Neuwald, I.J., Knepper, T.P., Anal. Bioanal. Chem. 2020, 412, 4763–4784. https://doi.org/10.1007/s00216-020-02520-z.
[2] Schorr, J, Therampilly, S., Jiao, L, Longree, P., Singer, H., Hollender, J. Stoten 2023, 889, 164170, http://dx.doi.org/10.1016/j.scitotenv.2023.164170
Persistent and mobile (PM), and very persistent and very mobile (vPvM) substances pose a threat to the water cycle but are often not covered in conventional environmental monitoring programs. PM substances that enter surface waters through
agricultural runoff and wastewater discharges can penetrate natural barriers such as soil and riverbanks, reach groundwater resources, and even pass drinking water treatment steps including activated carbon or ozonation. Many PM substances are not
covered by routine reversed-phase solid phase extraction followed by reverse-phase liquid chromatography coupled to mass spectrometry [1].
In this presentation, enrichment steps and chromatographic separations such as anion chromatography [2], hydrophilic interaction chromatography and mixed-mode liquid chromatography suitable for monitoring of anionic and small neutral PM substances
such as pesticide transformation products and industrial contaminants will be discussed. Coupling with high resolution mass spectrometry enables an expansion from target to suspect and non-target screening, closing the monitoring gap. The challenges and limitations of the methods will be illustrated using various water samples.
Literature:
[1] Zahn, D., Neuwald, I.J., Knepper, T.P., Anal. Bioanal. Chem. 2020, 412, 4763–4784. https://doi.org/10.1007/s00216-020-02520-z.
[2] Schorr, J, Therampilly, S., Jiao, L, Longree, P., Singer, H., Hollender, J. Stoten 2023, 889, 164170, http://dx.doi.org/10.1016/j.scitotenv.2023.164170
