Lipid metabolites beyond triglycerides and cholesterol have vast potential for applications in clinical diagnostics, with substantial societal and economical value. To successfully evolve from the current research-grade methods to assays suitable for routine clinical applications, a harmonization - if not standardization - of these mass spectrometry-based workflows is necessary.
This presentation is intended to provide an overview of international efforts to tackle the issues of workflow harmonization, and to serve as an open invitation for others to join this growing community. Specifically, past and planned interlaboratory ring trials for select lipids with potential for clinical diagnostics will be discussed.
Keywords: clinical translation, plasma lipidomics, harmonization, ring trials
