Lecture
LCxSFC coupling: A robust tool to aid understanding of renewable and circular industrial processes
- at -
- ICM Saal 5
- Type: Lecture
Lecture description
Biomass conversion and the use of recycled materials produce highly complex molecular mixtures that must be thoroughly characterized to optimize processing before incorporation into final products. Molecular analysis is crucial at every stage, yet it poses a significant challenge due to the inherent complexity of these mixtures.
Here, we present the development of a multidimensional separation instrument that combines liquid chromatography and supercritical fluid chromatography. This technology enables the separation of mixtures containing hundreds of non-volatile molecules, including the numerous isomers typically found in such matrices. When coupled with high-resolution mass spectrometry, the system can propose structural candidates or track specific target compounds.
We will showcase our technologies through practical examples, including the analysis of hydrothermal liquefaction effluents derived from algae, the study of lignin oligomers, and the monitoring of bio-based material incorporation in lubricant formulations.
Literature:
[1] M. Sanchez, J. Crépier, K. Faure, LCGC Supplements (2025) 14–20.
[2] E.Tammekivi, M. Batteau, D. Laurenti, K. Faure, Analytica Chimica Acta 1288 (2024) 342157
Here, we present the development of a multidimensional separation instrument that combines liquid chromatography and supercritical fluid chromatography. This technology enables the separation of mixtures containing hundreds of non-volatile molecules, including the numerous isomers typically found in such matrices. When coupled with high-resolution mass spectrometry, the system can propose structural candidates or track specific target compounds.
We will showcase our technologies through practical examples, including the analysis of hydrothermal liquefaction effluents derived from algae, the study of lignin oligomers, and the monitoring of bio-based material incorporation in lubricant formulations.
Literature:
[1] M. Sanchez, J. Crépier, K. Faure, LCGC Supplements (2025) 14–20.
[2] E.Tammekivi, M. Batteau, D. Laurenti, K. Faure, Analytica Chimica Acta 1288 (2024) 342157
