Lecture
GC-Based hyphenated techniques for detailed characterization of complex samples
- at -
- ICM Saal 5
- Type: Lecture
Lecture description
G. Purcaro, Gembloux, D.Eggermont, Gembloux, A.Gorska, Gembloux
Food analysis is increasingly moving beyond single parameter approaches toward integrated strategies capable of capturing the full complexity of real samples. This evolution calls for analytical solutions that combine high selectivity, sensitivity, and information content, while remaining applicable to routine and industrial workflows.
In this context, GC-based hyphenated chromatographic techniques have become powerful tools for the detailed characterization of complex food matrices.
Configurations such as GC–GC and comprehensive two-dimensional GC (GC×GC), as well as LC–GC(×GC) couplings, enable both targeted and untargeted profiling within a single analytical platform. These approaches provide enhanced separation power and chemically meaningful fingerprints, supporting reliable assessment of food quality, authenticity, and safety.
This presentation will illustrate the practical benefits of GC-based hyphenated techniques through selected case studies. The capability of GC×GC to generate information-rich chromatographic fingerprints will be demonstrated. The synergistic role of GC×GC in simplifying sample preparation will be discussed. Finally, the advantages of combining pre-fractionation by LC with GC and GC×GC will be highlighted in the analysis of food contaminants, with particular emphasis on mineral oil hydrocarbons.
Overall, the lecture aims to show how GC-based hyphenated techniques can deliver actionable, high-value analytical information, bridging advanced separation science and real-world food analysis needs.
Food analysis is increasingly moving beyond single parameter approaches toward integrated strategies capable of capturing the full complexity of real samples. This evolution calls for analytical solutions that combine high selectivity, sensitivity, and information content, while remaining applicable to routine and industrial workflows.
In this context, GC-based hyphenated chromatographic techniques have become powerful tools for the detailed characterization of complex food matrices.
Configurations such as GC–GC and comprehensive two-dimensional GC (GC×GC), as well as LC–GC(×GC) couplings, enable both targeted and untargeted profiling within a single analytical platform. These approaches provide enhanced separation power and chemically meaningful fingerprints, supporting reliable assessment of food quality, authenticity, and safety.
This presentation will illustrate the practical benefits of GC-based hyphenated techniques through selected case studies. The capability of GC×GC to generate information-rich chromatographic fingerprints will be demonstrated. The synergistic role of GC×GC in simplifying sample preparation will be discussed. Finally, the advantages of combining pre-fractionation by LC with GC and GC×GC will be highlighted in the analysis of food contaminants, with particular emphasis on mineral oil hydrocarbons.
Overall, the lecture aims to show how GC-based hyphenated techniques can deliver actionable, high-value analytical information, bridging advanced separation science and real-world food analysis needs.
