Lecture
Bunsen-Kirchhoff Award Ceremony and Awardee Presentation - Particles - Gotta Catch ’Em All! Pushing the Boundaries of Single Particle Methods
- at -
- ICM Saal 5
- Type: Award
Lecture description
Single particle ICP-MS has transformed our ability to interrogate complex particulate systems, offering highly sensitive and information-rich access to particles in a one-by-one fashion. Yet its applicability remains constrained by inherent limitations. These become particularly evident when targeting particles at both ends of the analysable size range, with heterogeneous compositions and chemically relevant molecular identities. At the same time, the increasing scale and complexity of single particle datasets place growing demands on data treatment, interpretation and analytical confidence.
This presentation explores novel strategies to expand the analytical scope of single particle analysis beyond mentioned boundaries. This includes approaches to retrieve molecular signatures and physical properties before particles are destroyed during ICP-MS analysis. In particular, complementary optical and spectroscopic methods, including in-line microscopy, Raman spectroscopy and trapping-based approaches, are introduced as routes to access particle-resolved information on size, morphology and chemical identity. In parallel, ICPTOFMS and a new data processing pipeline are highlighted as powerful tools for screening complex samples for relevant particle populations and enabling in-depth characterisation.
By combining rapid elemental screening with orthogonal particle-resolved techniques, we may open new avenues for the analysis of biologically, environmentally and industrially relevant particles in complex real-world samples with greater selectivity, accuracy and interpretative depth. Rather than viewing ICP-MS as a stand-alone technique, this presentation advocates an integrated analytical strategy for deciphering complex particulate systems.
This presentation explores novel strategies to expand the analytical scope of single particle analysis beyond mentioned boundaries. This includes approaches to retrieve molecular signatures and physical properties before particles are destroyed during ICP-MS analysis. In particular, complementary optical and spectroscopic methods, including in-line microscopy, Raman spectroscopy and trapping-based approaches, are introduced as routes to access particle-resolved information on size, morphology and chemical identity. In parallel, ICPTOFMS and a new data processing pipeline are highlighted as powerful tools for screening complex samples for relevant particle populations and enabling in-depth characterisation.
By combining rapid elemental screening with orthogonal particle-resolved techniques, we may open new avenues for the analysis of biologically, environmentally and industrially relevant particles in complex real-world samples with greater selectivity, accuracy and interpretative depth. Rather than viewing ICP-MS as a stand-alone technique, this presentation advocates an integrated analytical strategy for deciphering complex particulate systems.
